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Table 1 Gene ontology functional terms and their respective significances under the standard (unweighted) and the weighted tests obtained for the HPV experiment [19] with the permutation test.

From: Gene set internal coherence in the context of functional profiling

   

Weighted

Unweighted

GO name

BP

size

Log Odds

p-value

Adjusted

p-value

Log Odds

p-value

Adjusted

p-value

negative regulation of protein kinase activity

GO:0006469

100

3.030

<0.001

<0.001

2.548

0.006

0.083

DNA replication initiation

GO:0006270

44

4.281

<0.001

<0.001

4.162

<0.001

<0.001

SRP-dependent cotranslational protein targeting to membrane

GO:0006614

12

4.103

<0.001

<0.001

4.032

<0.001

<0.001

DNA strand elongation

GO:0006271

13

4.079

<0.001

<0.001

3.945

<0.001

<0.001

regulation of smooth muscle contraction

GO:0006940

18

2.875

0.010

0.088

3.597

<0.001

<0.001