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Table 3 Most significant GO categories in ulcerative IC

From: Gene expression profile of bladder tissue of patients with ulcerative interstitial cystitis

result file

term

ID

count

size

p-value

corrected p-value*

biological processes up

immune system process

GO:0002376

217

551

1.07E-77

1.88E-74

 

immune response

GO:0006955

180

418

4.21E-71

7.41E-68

 

response to stimulus

GO:0050896

308

1397

1.36E-44

2.39E-41

 

defense response

GO:0006952

117

325

2.19E-36

3.84E-33

 

signal transduction

GO:0007165

348

2177

1.36E-20

2.39E-17

 

cell communication

GO:0007154

371

2387

5.63E-20

9.89E-17

 

inflammatory response

GO:0006954

66

195

3.71E-19

6.51E-16

biological processes down

transmembrane receptor protein serine/threonine kinase signaling pathway

GO:0007178

18

55

1.99E-07

3E-04

molecular functions up

signal transducer activity

GO:0004871

234

1200

1.48E-25

1.17E-22

 

receptor activity

GO:0004872

170

854

3.00E-19

2.35E-16

molecular functions down

sequence-specific DNA binding

GO:0043565

46

293

1.32E-05

0.0104

cellular components up

plasma membrane

GO:0005886

228

1304

3.27E-18

1.26E-15

cellular components down

none

-

-

-

-

-

  1. * Up-regulated GO categories with a corrected p-value < 1.3E-15 are listed, the top-down regulated GO category of the respective analysis is shown. For "cellular components down" no significant GO category has been found.