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Table 1 Differentially expressed genes detected over the trypanosome infection time course and between breeds.

From: Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility

Comparison/contrast

Unexpressed

Unchanged

Increased expression

Decreased expression

% of

microarray DEb

Boran: 14 vs 0 dpi

2,693

5,217

2

8

0.1

Boran: 21 vs 0 dpi

2,511

5,352

11

46

0.7

Boran: 25 vs 0 dpi

2,888

4,845

58

129

2.4

Boran: 29 vs 0 dpi

2,220

5,653

10

37

0.6

Boran: 34 vs 0 dpi

2,164

5,528

37

191

2.9

N'Dama: 14 vs 0 dpi

2,287

5,552

30

51

1.0

N'Dama: 21 vs 0 dpi

2,620

4,353

431

516

12.0

N'Dama: 25 vs 0 dpi

2,551

4,510

393

466

10.8

N'Dama: 29 vs 0 dpi

1,909

5,940

26

45

0.9

N'Dama: 34 vs 0 dpi

2,871

5,012

16

21

0.5

N'Dama vs Boran: 0 dpi

2,628

5,078

136

78

2.7

N'Dama vs Boran: 14 dpi

2,360

5,542

5

13

0.2

N'Dama vs Boran: 21 dpi

2,509

5,398

7

6

0.2

N'Dama vs Boran: 25 dpi

2,754

5,008

112

46

2.0

N'Dama vs Boran: 29 dpi

1,805

6,104

4

7

0.1

N'Dama vs Boran: 34 dpi

2,189

5,435

145

151

3.7

  1. a DE: Differentially expressed
  2. Expressed genes are defined as those having foreground ≥ background +2 SD in ≥ 50% of microarrays in any group of microarrays for a contrast.
  3. Numbers of differentially expressed genes (P ≤ 0.05) are based on a total of 7,920 genes and are FDR-adjusted.
  4. For the between breed contrasts, increased expression indicates higher in N'Dama compared to Boran and decreased expression indicates higher in Boran compared to N'Dama.