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Figure 3 | BMC Genomics

Figure 3

From: BioQuali Cytoscape plugin: analysing the global consistency of regulatory networks

Figure 3

Fatty acid metabolism, initial model. Fatty acid synthesis in chicken liver is taken from the literature; only the most important biological entities are represented. After checking the consistency of this model with transcriptomic data detailed in Table 1 (up/down-regulation are represented by nodes with a green/red border respectively), the BioQuali plugin detected a local inconsistency (LI) highlighted in yellow in the graph. The reasoning behind this LI is that SREBF1 is observed in the dataset as down-regulated (-1.1) while its only activator is observed up-regulated, thus, the model should be completed in order to explain SREBF1's observation.

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