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Table 1 Enrichment analysis

From: In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach

Term

Count

%

PValue

GO:0007275~multicellular organismal development

18

54.55%

0.000000

GO:0003700~transcription factor activity

12

36.36%

0.000000

GO:0009653~anatomical structure morphogenesis

16

48.48%

0.000000

GO:0032502~developmental process

20

60.61%

0.000000

GO:0009790~embryonic development

10

30.30%

0.000000

GO:0048856~anatomical structure development

17

51.52%

0.000000

GO:0030528~transcription regulator activity

13

39.39%

0.000002

GO:0030154~cell differentiation

15

45.45%

0.000002

GO:0048869~cellular developmental process

15

45.45%

0.000002

GO:0007389~pattern specification process

6

18.18%

0.000010

GO:0032501~multicellular organismal process

19

57.58%

0.000019

GO:0045165~cell fate commitment

5

15.15%

0.000022

GO:0043565~sequence-specific DNA binding

8

24.24%

0.000029

GO:0003677~DNA binding

14

42.42%

0.000051

GO:0031323~regulation of cellular metabolic process

16

48.48%

0.000063

GO:0019222~regulation of metabolic process

16

48.48%

0.000095

GO:0009887~organ morphogenesis

7

21.21%

0.000105

GO:0031325~positive regulation of cellular metabolic process

7

21.21%

0.000107

GO:0009893~positive regulation of metabolic process

7

21.21%

0.000154

GO:0001824~blastocyst development

3

9.09%

0.000356

GO:0045449~regulation of transcription

14

42.42%

0.000413

GO:0019219~regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

14

42.42%

0.000519

GO:0050789~regulation of biological process

19

57.58%

0.000533

GO:0065007~biological regulation

20

60.61%

0.000539

GO:0006350~transcription

14

42.42%

0.000597

GO:0009798~axis specification

3

9.09%

0.000640

GO:0050794~regulation of cellular process

18

54.55%

0.000754

GO:0010468~regulation of gene expression

14

42.42%

0.000756

GO:0006355~regulation of transcription, DNA-dependent

13

39.39%

0.000890

  1. Top enriched gene ontology categories for the 33 OCT4 target genes as received by DAVID [25] (see Additional file 2 for the complete results).