Table 2 MT Regulators and Associated Protein Profiles
Functional Class | Common Name | Gene Name | Fold Change |
|---|---|---|---|
MT Polymerization Regulators | |||
| Â | EB2 | mapre2 | 1.20 |
| Â | MAP1A | mtap1 | 1.47 |
| Â | MAP1B | mtap1b | 1.27 |
| Â | MAP2 | mtap2 | -1.63 |
Stabilizers/Assembly Promoters | MAP4 | mtap4 | 1.24 |
| Â | CLASP1 | Clasp1 | -1.19 |
| Â | MACF2/BPAG1 | Dst | -1.29 |
| Â | STOP | mtap6 | -1.16 |
| Â | YB-1 | Ybx1 | -1.24 |
| Â | Dia2 | Diap2 | -1.19 |
| Â | RHAMM | Hmmr | -1.57 |
Mitosis-specific stabilizers | TACC3 | Tacc3 | -1.17 |
| Â | TPX2 | Tpx2 | -1.29 |
| Â | SCG10 | stmn2 | -2.44 |
Destabilizers/Disassembly Promoters | RB3 | stmn4 | 2.26 |
| Â | Kif2A | Kif2a | -1.22 |
| Â | Kif18A | Kif18a | -1.62 |
MT Severing Proteins | |||
| Â | Katanin p60 | katnal2 | -1.37 |
| Â | Fidgetin | Fign | -1.92 |
MT Nucleators | |||
| Â | gamma-tubulin 2 | Tubg2 | 1.27 |
| Â | GCP3 | Tubgcp3 | -1.18 |
MT-based Motors | |||
| Â | Kif11 | Kif11 | -1.24 |
| Â | Kif15 | Kif15 | -1.45 |
| Â | Kif18a | Kif18a | -1.62 |
| Â | Kif1a | Kif1a | 1.77 |
| Â | Kif20a | Kif20a | -1.15 |
| Â | Kif21a | Kif21a | -1.74 |
Kinesins | Kif21b | Kif21b | 4.60 |
| Â | Kif22 | Kif22 | -1.19 |
| Â | Kif26a | Kif26a | 2.32 |
| Â | Kif26b | Kif26b | 3.24 |
| Â | Kif2a | Kif2a | -1.22 |
| Â | Kif4 | Kif4 | -1.27 |
| Â | Kif9 | Kif9 | 1.15 |
| Â | dynein axonemal LC4 | Dnalc4 | 1.26 |
| Â | cytoplasmic dynein 1 IC1 | Dync1i1 | -1.29 |
Dyneins | cytoplasmic dynein 1 LIC1 | Dync1li1 | -1.18 |
| Â | cytoplasmic dynein 1 LIC2 | Dync1li2 | 1.20 |
| Â | dynein LC8-type2 | Dynll2 | -1.18 |