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Table 2 List of the genes down-regulated by enteric glial cells in intestinal epithelial cells.

From: Regulation of intestinal epithelial cells transcriptome by enteric glial cells: impact on intestinal epithelial barrier functions

Gene Symbol

Genbank

Description

% down-regulation (/control)

Fold difference

CARD12

AF376061

caspase recruitment domain family, member 12

83,43

6,04

KLK14

NM_022046

kallikrein 14

62,46

2,66

FGFR2

NM_022970

fibroblast growth factor receptor 2

57,12

2,33

BDP1

NM_018429

B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

56,58

2,30

SFRP4

NM_003014

secreted frizzled-related protein 4

55,26

2,24

C6

NM_000065

complement component 6

54,78

2,21

PRKCD

NM_006254

protein kinase C, delta

54,67

2,21

/

XM_066534

Homo sapiens diacylglycerol kinase, kappa (DGKK), mRNA.

52,44

2,10

C20orf133

NM_001033086

chromosome 20 open reading frame 133

52,36

2,10

PRKCQ

NM_006257

protein kinase C, theta

50,50

2,02

CDK5R1

NM_003885

cyclin-dependent kinase 5, regulatory subunit 1 (p35)

50,42

2,02

RPP40

NM_006638

ribonuclease P 40 kDa subunit

47,41

1,90

SLC30A1

AF323590

solute carrier family 30 (zinc transporter), member 1

46,22

1,86

TIMM8A

NM_004085

translocase of inner mitochondrial membrane 8 homolog A (yeast)

41,07

1,70

EBNA1BP2

NM_006824

EBNA1 binding protein 2

36,39

1,57

ITGAE

NM_002208

integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)

36,17

1,57

NOL1

NM_006170

nucleolar protein 1, 120 kDa

33,86

1,51

C6orf66

NM_014165

chromosome 6 open reading frame 66

33,81

1,51

NOL5A

NM_006392

nucleolar protein 5A (56 kDa with KKE/D repeat)

33,30

1,50

BAG1

U46917

BCL2-associated athanogene

32,19

1,47

/

AF123534

nucleolar protein NOP5/NOP58

32,14

1,47

ASAH1

AK025211

N-acylsphingosine amidohydrolase (acid ceramidase) 1

29,98

1,43

TINAGL1

AF236150

tubulointerstitial nephritis antigen-like 1

29,62

1,42

AADAC

NM_001086

arylacetamide deacetylase (esterase)

29,48

1,42

HSPA14

AF112210

heat shock 70 kDa protein 14

29,34

1,42

PSMC6

NM_002806

proteasome (prosome, macropain) 26S subunit, ATPase, 6

29,31

1,41

HNRPDL

D89678

heterogeneous nuclear ribonucleoprotein D-like

28,40

1,40

SAMHD1

NM_015474

SAM domain and HD domain 1

28,12

1,39

TP53RK

NM_033550

TP53 regulating kinase

26,99

1,37

MARK2

NM_004954

MAP/microtubule affinity-regulating kinase 2

26,41

1,36

CCR9

NM_031200

chemokine (C-C motif) receptor 9

24,74

1,33

RGL1

NM_015149

ral guanine nucleotide dissociation stimulator-like 1

24,20

1,32

E2F1

NM_005225

E2F transcription factor 1

23,90

1,31

PSMC1

NM_002802

proteasome (prosome, macropain) 26S subunit, ATPase, 1

23,75

1,31

IMP3

NM_018285

IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)

23,48

1,31

RNU3IP2

BC023662

RNA, U3 small nucleolar interacting protein 2

23,41

1,31

SMAD3

NM_005902

SMAD, mothers against DPP homolog 3 (Drosophila)

21,49

1,27

GPX2

NM_002083

glutathione peroxidase 2 (gastrointestinal)

21,27

1,27

LSP1

NM_002339

lymphocyte-specific protein 1

21,21

1,27

FGG

NM_021870

fibrinogen gamma chain

18,37

1,23

C20orf94

NM_001009608

chromosome 20 open reading frame 94

16,04

1,19

PPIL1

NM_016059

peptidylprolyl isomerase (cyclophilin)-like 1

14,74

1,17

HOXB2

NM_002145

homeobox B2

13,91

1,16

APOH

NM_000042

apolipoprotein H (beta-2-glycoprotein I)

13,17

1,15

PRSS23

NM_007173

protease, serine, 23

10,41

1,12

IARS2

NM_018060

isoleucine-tRNA synthetase 2, mitochondrial

10,02

1,11