Table 4 Lists of differentially expressed genes involved in cellular and molecular functions regulated in intestinal epithelial cells by enteric glial cells.
Ingenuity© cellular and molecular functions | Genes list | Score |
|---|---|---|
RNA Post-Transcriptional Modification | NOP5/NOP58, NOL5A, EBNA1BP2, RNU3IP2, IMP3 | 5.17 |
Cell Death | GPX2, SAT, PRKCD, B4GALT5, TXNIP, TOP2A, CDH1, PKN2, ASAH1, LSP1, BNIP3L, NPPB, CDK5R1, ANKRD1, VIP, CASP4, GLRX, FGFR2, KRT18, BAG1, PRKCQ, BTG1, PPARG, C6ORF66, SLC2A1, CARD12, SMAD3, FTH1, LAMA5, PTK2, IL18, MLLT3, FN1, PLAC8, KRT8, TGFBI, BNIP3, E2F1, SFRP4 | 4.85 |
Cell-To-Cell Signaling and Interaction | APOH, PRKCD, SMAD3, CDH1, PKN2, LAMA5, PTK2, VIP, IL18, FN1, FGG, KRT8, KRT18, BAG1, ITGAE, LAMC1, PPARG, TGFBI, E2F1 | 3.92 |
Cellular Development | SMAD3, PRKCD, CDH1, LAMA5, VIP, PTK2, IL18, CDK5R1, FGFR2, FN1, PLAC8, PRKCQ, LAMC1, PPARG, E2F1 | 3.92 |
Cell Morphology | SMAD3, PRKCD, CDH1, LAMA5, LSP1, DCTN2, VIP, IL18, PTK2, CDK5R1, FN1, KRT8, KRT18, PPARG, TGFBI, E2F1 | 3.88 |
Cellular Assembly and Organization | APOH, PRKCD, SMAD3, TOP2A, CDH1, DCTN2, EBNA1BP2, NPPB, PTK2, CDK5R1, HCAP-D3, FN1, FGG, KRT8, KRT18, MARK2, LAMC1, PPARG, BNIP3, E2F1 | 3.88 |
Carbohydrate Metabolism | FN1, B4GALT5, NPPB, PTK2, IL18 | 3.11 |
Cellular Movement | HOXB2, CCR9, C6, B4GALT5, SMAD3, PRKCD, MGLL, CDH1, LSP1, LAMA5, DCTN2, NPPB, CDK5R1, VIP, PTK2, IL18, FN1, BAG1, ITGAE, PPARG, TGFBI | 3.08 |
Cellular Growth and Proliferation | SAT, PRKCD, TXNIP, SMAD3, CDH1, FTH1, LAMA5, SLC30A1, EBNA1BP2, VIP, IL18, PTK2, MLLT3, FGFR2, FN1, PLAC8, BAG1, PRKCQ, BTG1, LAMC1, PPARG, BNIP3, E2F1, SFRP4 | 3.05 |
Cell Cycle | HCAP-D3, FN1, TXNIP, PRKCD, TOP2A, DCTN2, PPARG, EBNA1BP2, E2F1, VIP | 2.57 |
Molecular Transport | FGFR2, SAT, FN1, PRKCD, MGLL, BAG1, FTH1, PPARG, NPPB, PTK2, VIP, IL18 | 2.45 |
Nucleic Acid Metabolism | SAT, BAG1, NPPB, VIP | 2.45 |
Small Molecule Biochemistry | APOH, SAT, PRKCD, B4GALT5, MGLL, FTH1, ASAH1, NPPB, PTK2, IL18, VIP, ASS, GLRX, FGFR2, FN1, BAG1, PPARG | 2.45 |
Cellular Function and Maintenance | CCR9, SMAD3, CDH1, SLC30A1, PTK2, IL18, CDK5R1, FN1, FGG, KRT18, ITGAE, PPARG, BNIP3 | 2.25 |
DNA Replication, Recombination, and Repair | HCAP-D3, FN1, SMAD3, PRKCD, TOP2A, FTH1, DCTN2, EBNA1BP2 | 2.17 |
Gene Expression | APOH, SMAD3, PRKCD, CDH1, PKN2, VIP, IL18, FN1, BAG1, PRKCQ, RNF4, PPARG, E2F1 | 2.13 |
Cell Signaling | ASS, FN1, PRKCD, PPARG | 2.02 |
Amino Acid Metabolism | ASS, FTH1 | 1.94 |
Cellular Compromise | PRKCD, KRT18, TIMM8A, PPARG, E2F1 | 1.94 |
Drug Metabolism | GLRX, FTH1, NPPB, IL18, VIP | 1.94 |
Lipid Metabolism | FGFR2, APOH, SAT, FN1, MGLL, ASAH1, PPARG, NPPB, VIP | 1.94 |
Post-Translational Modification | PRKCD, BAG1, PRKCQ | 1.94 |
Protein Folding | BAG1 | 1.94 |
Protein Synthesis | BAG1, IL18 | 1.94 |
Vitamin and Mineral Metabolism | FGFR2, FTH1, PPARG | 1.94 |