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Figure 3 | BMC Genomics

Figure 3

From: Correlation of microsynteny conservation and disease gene distribution in mammalian genomes

Figure 3

There is a significant correlation between microsynteny and density of disease-gene orthologs over the mouse genome as a whole. Panel A: The number of conserved genes plotted against the number of disease genes for 20 Mb sliding windows of the mouse genome. Note the fit with the regression line (Pearson's R = 0.90, P < 1 × 10-6). Panel B: The relationship between the proportion of genes with conserved microsynteny (number of conserved genes per window/total genes per window) and the proportion of genes with disease orthologs (number of disease-related genes/total genes per window). The correlation for the whole mouse genome is significant (Pearson's R = 0.40, P < 4.0 × 10-4).

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