Skip to main content
Figure 4 | BMC Genomics

Figure 4

From: Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells

Figure 4

Cellular processes overrepresented by the mRNAs detected in microvesicles. A) A GO tree obtained from BiNGO showing the hierarchy of GOBPs overrepresented by mRNAs present in microvesicles (P < 0.05; see the color bar). Node colors represent the statistical significance of functional enrichment of the corresponding GOBPs. The white nodes (P > 0.05) were added to show the relationships among their downstream nodes. The overrepresented GOBPs were categorized into several groups of cellular processes, each of which is indicated by a box. B) The four GOBP groups (cell cycle, apoptosis, intracellular signaling, and intracellular transport) related to tumor progression are shown in detail.

Back to article page