Figure 4
From: Genome response to tissue plasminogen activator in experimental ischemic stroke
Analysis of gene probes differentially regulated in the blood of rats with permanent-MCAO without reperfusion (p ≤ 0.01, fold change ≥ |1.2|). (4a) Hierarchical cluster plot showing gene probes clustering by treatment with tPA. (4b) Cross-validation with Prediction Analysis of Microarrays (PAM) of gene probes differentially regulated by tPA. The 62 gene probes correctly predict treatment with tPA. (Rats not treated with tPA are shown on the x-axis by numbers 1-6, rats treated with tPA are number 7-12; y-axis represents the cross-validated probability of the predicted class)