Figure 6From: Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemiaApplication of in silico and experimental masks. MvA plots comparing expression differences with expression averages for all transcript clusters. Expression signals from ALL-16 xenografts ALL.100 (100% human) (n = 8) versus ALL.90 (90% human) (n = 3) were compared following the application of the A experimental B in silico or C combined masking approaches. Transcript clusters identified as susceptible to cross-species hybridisation are shown in black (.) all others are grey (.). Plots were generated using RMA normalised log2 signal intensities, lines represent 2-fold difference (log2 = 1).Back to article page