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Figure 6 | BMC Genomics

Figure 6

From: Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia

Figure 6

Application of in silico and experimental masks. MvA plots comparing expression differences with expression averages for all transcript clusters. Expression signals from ALL-16 xenografts ALL.100 (100% human) (n = 8) versus ALL.90 (90% human) (n = 3) were compared following the application of the A experimental B in silico or C combined masking approaches. Transcript clusters identified as susceptible to cross-species hybridisation are shown in black (.) all others are grey (.). Plots were generated using RMA normalised log2 signal intensities, lines represent 2-fold difference (log2 = 1).

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