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Table 2 Significance values (unadjusted and Bonferroni corrected P values) for the top SNPs associated with optimum race distance.

From: A genome-wide SNP-association study confirms a sequence variant (g.66493737C>T) in the equine myostatin (MSTN) gene as the most powerful predictor of optimum racing distance for Thoroughbred racehorses

CHR

SNP

UNADJ P

BONF. P

A1

A2

A11

A12

A22

18

g.66493737C>T

1.02E-10

N/A

T

C

0.1538

0.5962

0.2500

18

BIEC2-417495

1.61E-09

6.58E-05

T

C

0.1709

0.5983

0.2308

18

BIEC2-417423

3.55E-08

0.001454

G

A

0.1017

0.5169

0.3814

18

BIEC2-417372

6.21E-08

0.002545

G

A

0.0932

0.5424

0.3644

18

BIEC2-417274

8.08E-08

0.003312

T

G

0.1864

0.6017

0.2119

18

BIEC2-417210

3.13E-07

0.01281

C

T

0.2119

0.5763

0.2119

18

BIEC2-417524

4.87E-07

0.01995

G

A

0.1186

0.5763

0.3051

18

BIEC2-417507

5.09E-07

0.02086

C

A

0.1368

0.5897

0.2735

  1. A11: genotype frequency for homozygotes (allele 1) in the population (n = 118); A12: genotype frequency for heterozygotes; A22 genotype frequency for homozygotes (allele 2). Correction for multiple testing was not applied for g.66493737C>T; however, the association remains stronger (PBonf. = 4.18 × 10-6) after application of a correction factor.