gene | direction | tissue | mechanism proposed | reference |
---|---|---|---|---|
CCDC80 | DOWN | rat epithelial cells neoplastically transformed by β-catenin. |  | [9] |
CCDC80 | DOWN | thyroid neoplastic cell lines and tissues | Â | [14] |
CCDC80 | DOWN | colon and pancreatic cancer cells. | mediates growth inhibition | [9] |
SRPX | DOWN | highly malignant human pulmonary neuroendocrine tumors. | Â | [10] |
SRPX | DOWN | prostate carcinomas. | Â | [89] |
SRPX | DOWN | colorectal neoplasms. | Â | [90] |
SRPX | DOWN | lung adenocarcinomas. | Â | [91] |
SRPX | DOWN | colon adenocarcinomas. | Â | [92] |
SRPX | DOWN | endothelial cells, myeloma | Â | [93] |
SRPX | DOWN | stromal fibroblast cells from liver metastases of colorectal cancer | Â | [94] |
SRPX | NA | SRPX knock-out mouse embryonic fibroblasts | involvement in the maturation process of autophagy | [13] |
SRPX | NA | malignant tumors including lymphomas, lung adenocarcinomas and hepatomas | Tumors appear in SRPX-knock out mice | [11] |
SRPX | NA | human cancer cell lines. | apoptosis induction in human cancer cell lines; both the P-DUDES and the sushi regions necessary | [12] |
SRPX2 | NA | endothelial cells | mediator of angiogenesis | [20] |
SRPX2 | NA | Â | ligand for uPAR | [19] |
SRPX2 | UP | gastric cancer | enhancing cellular migration and adhesion through FAK signaling | |
SRPX2 | UP | pro-B leukemia cells | Â | [5] |