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Table 1 Selected GO category and genes that are altered at 7 days denervation, and comparison with expression at 35 days.

From: Differential alterations in gene expression profiles contribute to time-dependent effects of nandrolone to prevent denervation atrophy

GO category

Gene Name

Gene Symbol

7 days (Nan vs Veh)

35 days (Nan vs Veh)

Calcium/calmodulin-mediated signaling

Thrombospondin 1

THBS1

-2.27

2.55

Muscle contraction

Galanin

GAL

-1.43

10.82

 

Tropomyosin 3, gamma

TPM3

-2.00

-1.12

Proteolysis

A disintegrin-like and metallopeptidse with thrombospondin type 1 motif, 1

ADAMTS1

-1.69

2.33

 

Serpin peptidase inhibitor, class E, member 1

SERPINE1

-2.86

3.09

Steroid_hormone_receptor_activity

Nuclear receptor subfamily 4, group A, member 1

NR4A1

-4.00

1.75

 

Nuclear receptor subfamily 4, group A, member 2

NR4A2

-1.89

2.12

 

Nuclear receptor subfamily 4, group A, member 3

NR4A3

-5.88

1.28

Transcription

Activating transcription factor 3

ATF3

-5.56

2.36

 

B-cell leukemia/lymphoma 6

BCL6_PREDICTED

-1.72

-1.06

 

Basic helix-loop-helix domain containing, class B3

BHLHB3

1.67

-1.05

 

B-cell translocation gene 2, anti-proliferative

BTG2

-2.63

1.58

 

Transcription factor 4

TCF4

-1.39

1.18

 

Transducin-like enhancer of split 1, homolog of Drosophila E(spl)

TLE1_PREDICTED

-1.75

-1.08

 

Splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)

SFRS10

1.55

-1.09

Ubiquitin -Proteasome Pathway

Ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)

UBE2E2

-1.32

-1.08

 

Ubiquitin specific protease 12

USP12_PREDICTED

-1.23

1.35

  1. Abbreviation: Nandrolone, Nan; Vehicle, Veh.