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Table 2 Comparision of the key families and genes involved in apoptosis in mammals, Drosophila, Nematode, Echinoids, silkworm and fish.

From: The genomic underpinnings of apoptosis in the silkworm, Bombyx mori

Species name Families/genes'name

Mammala

Fruit Fliesb

Nematodec

Echinoidsd

Silkworme

Fishf

TNFSFA

50

2

0

11

2

11

Caspase FamilyB

13

7

4

34

5

12

Bcl-2 FamilyC

about 20

2

3

10

1

13

Bir DomainD

7

4

2

7

4

5

RHGE

0

4 (each1)

0

0

1 (reaper)

0

P53F

1

1

1

1

1

1

Apaf-1G

1

1

1

1

1

1

  1. In this study Homo sapiens represents mammals, Drosophila melanogaster represents fruit flies, Caenorhabditis elegans represents nematodes, Strongylocentrotus purpuratus represents Echinoids, Bombyx mori represents silkworms, and Danio rerio represents fish. The TNF family comprised of the ligands and the correspondent receptor. aA data are from [76–78]; aB data are from [79]; bB, cB, bC and cC data are from [65] and [6]; dA-dD and fA-fC data are from [80] and [81], respectively. The other data are the results of BLAST searches with the database in NCBI.