From: Computational approaches for detecting protein complexes from protein interaction networks: a survey
Methods | Main contributions |
---|---|
MCODE [27] | MCODE pioneered the computational detection of protein complexes from PPI networks. |
MCL is a widely used method [33–36] with good convergence and robustness [32] | |
Krogan et al. [33] | They provided and exploited a comprehensive TAP dataset for computational protein complex detection. |
Gavin et al. [3] | In addition to providing a TAP dataset widely used for protein complex detection, they described the inherent organization of protein complexes with core-attachment structures. |
They systematically conducted cross-species analysis of PPI networks to derive evolutionary information for protein complex detection. |