Gene expression patterns in four brain areas associate with quantitative measure of estrous behavior in dairy cows

Table 3 Significantly enriched Gene Ontology Biological Process terms in the estrous behavior associated gene lists*

Gene Ontology Biological Process term	day0	day12	day0 + day12
Behavior related terms
regulation of female receptivity; reproductive behavior in a multicellular organism; female mating behavior; maternal aggressive behavior; maternal behavior; parental behavior	HC	DH	HC
grooming behavior			HC
locomotory behavior	AP⁺
behavior	AP⁺
Neurotransmission and signaling related terms
neurological system process	AP⁺
regulation of neurotransmitter levels	AP
transmission of nerve impulse	AP⁺
regulation of synaptic transmission	DH
cell surface receptor linked signal transduction		DH⁺
cell-cell signaling	HC⁺
second-messenger-mediated signaling			VH⁺
response to cAMP	DH
Wnt receptor signaling pathway	DH
phosphoinositide-mediated signaling			VH
Ion regulation related terms
ion transport	AP⁺
elevation of cytosolic calcium ion concentration			DH
negative regulation of ion transmembrane transporter activity	AM
cytosolic calcium ion homeostasis	AM

* Only terms with p < 0.10 and fdr <0.20 are included. Terms typical of other organs (these terms appeared here due to genes with different functions in different organs) have been removed from this summary table. Where the term is supported by 5 or more genes in the gene list, the corresponding brain area is followed by a ⁺sign whereas in cases where the term is supported by only 2-4 genes, the sign is absent.

ISSN: 1471-2164