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Table 1 Discovery set genes showing QPCR validated transcriptional differences between WT and KO (Gpr54 or Kiss1)

From: The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent

 

GKO vs WT

KKO vs WT

Gene Target

FC (95%CI)

Direction

FC (95%CI)

Direction

Abca8a

1.85 (1.33-2.59)

Up

1.97 (1.33-2.90)

Up

Esr1

1.62 (1.37-1.92)

Up

1.54 (1.32-1.78)

Up

Kiss1

14.03 (10.86-18.11)

Up

N.A.

N.A.

Mmp2

1.51 (1.18-1.94)

Up

n.s.

n.s.

Npas4

2.60 (2.09-3.25)

Up

n.s.

n.s.

Lrdd

n.s.

n.s.

1.80 (1.29-2.51)

Up

Tmem144

n.s.

n.s.

2.61 (2.21-3.08)

Up

  1. FC = fold change, CI = confidence interval, n.s. = not significant, N.A. = not applicable. GKO = GPR54 knockout, KKO = Kisspeptin knockout.
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BMC Genomics

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