Skip to main content

Table 2 Module-specific TFs according to the hypergeometric enrichment test (P < 0.05).

From: Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle

Modules

Number

Transcriptional Factors*

Cell Cycle

12

ARID5B ATF6**CHR CREB1 E2F1 HLTF NFYA NKX61 SP1 TGIF1 ZNF239 ZSCAN21

Fat

13

ABL1 CUX1 E4F1 ESRRB GATA2 IKZF1 MYT1L NKX25 PAX4 SOX2 TEF TFCP2 ZBTB7B

Immune

2

ETV4 YBX1

Mitochondria

9

CEBPZ GSH2 JUN MEF2C NFI NFAT5 POU3F1 SPZ1 XFD2

Muscle/Glycolysis

8

GLI1 HNF4A KLF10 MEIS1** NEUROG1** NFKB1 SMAD2 ZNF300

Ribosome

0

None

  1. *TFs in bold-face correspond to module-specific TFs that are significantly expressed in muscle (Figure 3C).
  2. **ATF6, NEUROG1 and MEIS1 are assigned to different modules depending on the statistical test employed, hypergeometric or odds ratio. For all other TFs, there was a perfect agreement between the two criteria (Table 3).