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Figure 8 | BMC Genomics

Figure 8

From: MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms

Figure 8

Fold enrichment of transcription factor binding to the region of the -1607 MMP1 promoter polymorphism. (a) Fold enrichment of c-Fos, ETS1 and ETS2 binding at the region of the -1607 promoter polymorphism relative to a region 5600 bases upstream of the promoter polymorphism. (b) Complete replication of experiment in 5a using cells from different 1G and 2G individuals. (c) Fold enrichment of GATA3 binding at the region of the -1607 promoter polymorphism relative to a region 5600 bases upstream of the promoter polymorphism. (d) Replication of experiment 5c. Input control refers to enrichment in the absence of any precipitating antibody.

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BMC Genomics

ISSN: 1471-2164

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