Skip to main content

Table 3 Top functions by pathway analysis (IPA)

From: HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis

 

CAM

Partek

Overlaps

CAM

Partek

Overlaps

 

2months

2months

2months

12months

12months

12months

Disease & Disorder-related Function

Inflammatory response

Inflammatory response

*Inflammatory response

Cancer

Cancer

Cancer

 

3.57 × 10-5 - 0.0320

1.61 × 10-5 - 0.0474

1.93 × 10-4 - 0.0474

2.71 × 10-7 -6.96 × 10-3

2.84 × 10-6 -3.44 × 10-3

1.77 × 10-5 -.0133

Molecular & Cellular Functions

*Cellular development

*Cellular function & maintenance

Cell-to-cell signaling & interaction

*Cellular development

*Cell cycle

*Cell cycle

 

3.58 × 10-7 -0.0326

1.87 × 10-6 - 0.0444

1.93 × 10-4 - 0.0488

7.10 × 10-13 -7.58 × 10-3

1.23 × 10-11 - 3.09 × 10-3

2.32 × 10-8 -.0133

Physiological System Development & Function

Hematological system development & function

Hematological system development & function

Hematological system development & function

Hematological system development & function

Cell-mediated immune response

Hematological system development & function

 

3.06 × 10-5 -0.0326

2.62 × 10-6 -0.0474

1.93 × 10-4 -0.0485

1.89 × 10-12 -7.26 × 10-3

1.27 × 10-7 -3.09 × 10-3

3.02 × 10-6 -.0133

  1. The top functions identified by Ingenuity Pathway Analysis from each category are shown and include: 1.) Diseases and Disorder-related Function, 2.) Molecular and Cellular Functions, and, 3.) Physiological System Development and Function. * denotes the top biologic function, defined as the function from all 3 categories with the most significant IPA score.