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Table 3 Sequence diversity and classification of A-superfamily conopeptides from Conus bullatus

From: Characterization of the Conus bullatus genome and its venom-duct transcriptome

Subclasses of A-superfamily peptides (Mature toxin sequences)

α4/4

  
 

Bu18

APGCC NNPAC VKHRC*

 

Bu20

DENGCC WNPSC PRPRC T*

α4/5

  
 

Bu21

CC WNRAC TRLVPC SK

α4/6

  
 

Bu22

GCC TYPPC AVLSPLC D

α4/7

  
 

Bu19

GCC HDIFC KHNNPDIC*

κA

  
 

Bu27

APELVVTATTTCC GYDPMTIC PPC MC THSC PPKRKP*

κA-like

  
 

Bu23

LNDLVPQYWTECC GRIGPHC SRC IC PEVVC PKN*

 

Bu24

   YWTECC GRIGPHC SRC IC PEVAC PKN*

 

Bu25

   YWTECC GRIGPHC SRC IC PGVVC PKR*

 

Bu26

LRECC GRVGPMC PKC MC PPRRC

  1. *C-terminal is amidated. We have assumed that the proteolytic cleavage site is at the basic residue proximal to the presumed toxin sequence.