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Table 4 Most abundant biological process GO annotations of nucleolar-associated proteins with reliability index above 10

From: PNAC: a protein nucleolar association classifier

Biological process GO term

Protein counta

Nucleolar-Enriched

RNA metabolic process (GO:0016070)

163

   of which rRNA processing (GO:0006364)

35

tRNA processing (GO:0008033)

27

Transcription, DNA-dependent (GO:0006351)

35

Cellular component organization (GO:0016043)

81

Ribosome biogenesis (GO:0042254)

50

   of which rRNA processing (GO:0006364)

35

Regulation of biological process (GO:0050789)

45

Nucleoplasmic-nucleolar

Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (GO:0006139)

118

   of which DNA repair (GO:0006281)

52

DNA replication (GO:0006260)

43

Regulation of biological process (GO:0050789)

107

   of which Regulation of transcription, DNA-dependent (GO:0006355)

35

Signal transduction (GO:0007165)

36

Cellular component organization (GO:0016043)

92

   of which Chromosome organisation (GO:0051276)

68

Cell cycle (GO:0007049)

89

Multicellular organismal development (GO:0007275)

40

Cell proliferation (GO:0008283)

39

Cell death (GO:0008219)

27

Nucleolar-cytoplasmic

Protein metabolic process (GO:0019538)

127

   of which Translation (GO:0006412)

106

Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (GO:0006139)

33

Regulation of biological process (GO:0050789)

27

   of which Signal transduction (GO:0007165)

10

Cellular component organisation (GO:0016043)

18

   of which Organelle organisation (GO:0006996)

11

  1. a count includes proteins annotated with child terms