Cluster 1 |
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•Inflammatory response [AGER, ALOX5, MYD88, SEPP1, SERPING1] |
•Regulation of cytoskeleton organization [ABLIM1, DES, DST, NEDD9, PALLD, PRF1] |
•Positive regulation of response to stimulus [C1QA, C1QB, C7, CADM1, CX3CL1, FABP4, FCER1G, MYD88, SERPING1, SLIT2] |
•Wound healing [CD36, GNAQ, HBEGF, MYH10, SERPING1, THBD, VWF] |
•Response to mechanical stimulus [BTG2,TIM2, CAV1,CCL2, MGP,TXNIP,TGFBR2, FOS] |
•Negative regulation of cell proliferation [SFTPD, VSIG4] |
•Regulation of locomotion [EGFL7,CLIC4,AGER, DLC1,ENPP2,EDN1, IL6, IL6ST, VCL] |
•Complement activation [C1QA, C1QB, C7, SERPING1] |
•Positive regulation of immune response [C1QA, C1QB, C7, CADM1, FCER1G, MYD88, SERPING1] |
•Hormonal immune response[C1QA, C1QB, C7, CCL2, IL6, SERPING1] 1, FCER1G, MYD88, SERPING1] |
Cluster 2 |
•M phase of mitotic cell cycle [AURKA, BIRC5, BUB1,CCNB1, CENPE] |
•Negative regulation of intracellular transport [BARD1, GSK3B, NCBP2, NF1, TACC3] |
•Microtubule-based process [CEP250, DST] |
•Response to DNA damage stimulus [CSNK1D, DDB1, NONO,POLD1, TOP2A] |
•Spindle organization [AURKA, BUB1B, CKS2, TTK, TUBG1, ZWINT] |
•Cellular protein localization [AP1B1, ARF5, ICMT, NUP62, TIMM13, TOM1L1] |
•DNA repair [APEX1, CSNK1D, DDB1, HMGB2,PARP1,POLB, POLD1,TOP2A] |
•Glycosylation[ALG6,FUT2,GALNT10,MGAT4B, OGT, STT3A, UGCGL1] |
Cluster 3 |
•Enzyme linked receptor protein signaling pathway [ADRB2, ARRB2,SPTBN1, TEK, TGFBR3, ZFP106] |
•Metal ion homeostasis [AGTR1, C5AR1, RGN, S1PR4, TRPC6] |
•Protein amino acid phosphorylation [AATK, ADRB2, TIE1, TTN, ULK2] |
•Transmembrane receptor protein tyrosine kinase signaling pathway [ADRB2, CRYAB, SORBS1, TEK, ZFP106] |
•Negative regulation of cell proliferation [ADAMTS8, AIF1, TENC1, TGFB1I1, TOB2] |
Cluster 4 |
•Collagen fibril organization [COL3A1, COL5A2] |
•Glycolysis[ALDOA, ENO1, GAPDH, PKM2, TPI1] |
•Carbohydrate catabolic process [ALDOA, ENO1, FUCA1, GAPDH, TPI1] |
•Extracellular structure organization [AGRN, COL11A1, COL3A1, COL5A2, ERBB2] |
•Collagen metabolic process [COL3A1, MMP1, MMP11, MMP7] |
•Negative regulation of cell adhesion [CDKN2A, HNRNPAB, TGFBI] |
•Generation of precursor metabolites and energy [ALDOA, ENO1, GAPDH, UQCRH, UQCRQ] |
•Negative regulation of protein ubiquitination [PSMA1,PSMA2, PSMB2, PSMB3, PSMB4, PSMB5] |