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Table 2 The HDAC inhibitor queries trichostatin A, vorinostat and valproic acid derived from the CMAP highly correlate with an HDAC inhibition experiment.

From: A searchable cross-platform gene expression database reveals connections between drug treatments and disease

 

trichostatin A

vorinostat

valproic acid

SAMPLE

R

N

r

N

r

N

GSM548552: 8146_vehicle control_2

-0.86

492

-0.89

494

-0.65

492

GSM548551: 8145_vehicle control_1

-0.85

490

-0.88

494

-0.62

491

GSM548546: 8140_LZ_2

0.65

491

0.62

492

0.50

485

GSM548545: 8139_LZ_1

0.66

491

0.61

489

0.52

485

GSM548547: 8141_SAHA_1

0.68

491

0.66

488

0.50

487

GSM548548: 8142_SAHA_2

0.70

492

0.70

489

0.51

485

GSM548550: 8144_FK228_2

0.72

493

0.79

488

0.40

484

GSM548549: 8143_FK228_1

0.75

492

0.81

484

0.45

484

pooled profiles

      

LZ v control

0.89

388

0.91

382

0.74

303

SAHA v control

0.90

374

0.92

368

0.74

290

FK228 v control

0.88

387

0.92

390

0.69

301

  1. The regression scores for the pooled treatment and control groups are shown at the bottom of the table.