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Table 3 List of paralogues identified in the gilthead sea bream skeletal muscle transcriptome

From: Fast skeletal muscle transcriptome of the Gilthead sea bream (Sparus aurata) determined by next generation sequencing

Paralogue Gene name

Gene Function

Fraction of CDS (%)

Paralogue1/ paralogue2

Coverage

Paralogue1/ Paralogue2

Paralogues identity (%)

Nomenclature

Acethylcoline receptor subunit alpha 1

Ion-conducting channel

50/50

8/12

85

Alpha 1.a/1.b

Adp/atp translocase (Solute carrier family 25, SLC25)

Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane

100/100

43/87

92

SLC25 member 5 and 6

Calpain small subunit 1

Calcium-regulated thiol-protease involved in cytoskeletal remodeling

100/100

10/11

79

Calpain subunit 1a/b

Carnitine O- acetyltransferase

Carnitine acetylase is specific for short chain fatty acids

100/67

23/7

67

Carnitine O-acetyltransferase a1/a2

Dehydrogenase reductase member 7c

Putative oxidoreductase

100/99

59/32

60

DHR7SC-A/DHR7SC-B

Dysferlin interacting protein 1

Sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes

90/90

39/11

71

Dysferlin1a/b

Epithelial membranse protein 3

Probably involved in cell proliferation and cell-cell interactions

100/100

4/14

68

EMP3a/b

Glioblastoma amplified sequence

Widely expressed. Most abundant in heart and skeletal muscle

100/100

39/10

80

Nipsnap2a/b

High mobility group box 1

DNA binding proteins that associates with chromatin

88/60/87

439/7/9

60

HMG1a/b HMG2

Microglobulin beta-2

Component of the class I major histocompatibility complex (MHC)

100/100

57/90

60

B2ma/b

Myomesin 185 kDa

Major component of the vertebrate myofibrillar M band

98/90

170/54

65

Myomesin1a/b

Serine threonine-protein phosphatase

Essential for cell division, and participates in muscle contractility and protein synthesis

50/50

3/4

89

Subunit alpha/gamma

Solute carrier family 38 member 5

Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides

100/90

14/5

73

Member 5a/b

Tyrosine 3 monooxigenase

Enzyme function

90/100

5/5

74

Ywhab/ywhag2

Set and mynd domain- containing protein 1

Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation

95/97

154/127

76

Smyd1a/b

Dual specificity phosphatase and pro Isomerase domain containing 1

Catalyse reaction: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

95/100

7/7

51

DUPD1a/b

Metalloproteinase inhibitor 2 precursor

Complexes with metalloproteinases and irreversibly inactivates them

80/60

4/4

62

TIMP2b/a

Retinoid x gamma

Rreceptor for retinoic acid

100/100

21/10

73

Gamma/beta

Junctophilin 1

Contributes to the stabilization of the junctional membrane complexes

85/87

7/10

65

Junctophilin 1a/b

60s ribosomal protein l5

Required for rRNA maturation and formation of the 60 S ribosomal subunits

100/100

58/186

91

Rpl5a/b

Trans-2,3-enoyl-CoA reductase

Reduces trans-2,3-stearoyl-CoA to stearoyl-CoA of long and very long chain fatty acids

98/98

11/61

75

Trec.a/b

Methylmalonate- semialdehyde Dehydrogenase

Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA

100/100

26/12

86

Aldha1.a/a1.b

Eukaryotic translation initiation factor 4e type 3

Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1

100/100

28/15

73

EIF4E3a/b

Fk506-binding protein 1a

May play a role in modulation of ryanodine receptor isoform-1 (RYR-1)

100/100

52/12

82

FKBP1A.1/A.2

Splicing arginine serine-rich 11

May function in pre-mRNA splicing.

95/95

11/25

82

Srf11a/b

Kelch repeat and btb domain containing 10

Substrate-specific adapter of an E3 ubiquitin-protein ligase complex

95/100

38/15

53

Kbtb5/kbtb10