Paralogue Gene name | Gene Function | Fraction of CDS (%) Paralogue1/ paralogue2 | Coverage Paralogue1/ Paralogue2 | Paralogues identity (%) | Nomenclature |
---|---|---|---|---|---|
Acethylcoline receptor subunit alpha 1 | Ion-conducting channel | 50/50 | 8/12 | 85 | Alpha 1.a/1.b |
Adp/atp translocase (Solute carrier family 25, SLC25) | Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane | 100/100 | 43/87 | 92 | SLC25 member 5 and 6 |
Calpain small subunit 1 | Calcium-regulated thiol-protease involved in cytoskeletal remodeling | 100/100 | 10/11 | 79 | Calpain subunit 1a/b |
Carnitine O- acetyltransferase | Carnitine acetylase is specific for short chain fatty acids | 100/67 | 23/7 | 67 | Carnitine O-acetyltransferase a1/a2 |
Dehydrogenase reductase member 7c | Putative oxidoreductase | 100/99 | 59/32 | 60 | DHR7SC-A/DHR7SC-B |
Dysferlin interacting protein 1 | Sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes | 90/90 | 39/11 | 71 | Dysferlin1a/b |
Epithelial membranse protein 3 | Probably involved in cell proliferation and cell-cell interactions | 100/100 | 4/14 | 68 | EMP3a/b |
Glioblastoma amplified sequence | Widely expressed. Most abundant in heart and skeletal muscle | 100/100 | 39/10 | 80 | Nipsnap2a/b |
High mobility group box 1 | DNA binding proteins that associates with chromatin | 88/60/87 | 439/7/9 | 60 | HMG1a/b HMG2 |
Microglobulin beta-2 | Component of the class I major histocompatibility complex (MHC) | 100/100 | 57/90 | 60 | B2ma/b |
Myomesin 185 kDa | Major component of the vertebrate myofibrillar M band | 98/90 | 170/54 | 65 | Myomesin1a/b |
Serine threonine-protein phosphatase | Essential for cell division, and participates in muscle contractility and protein synthesis | 50/50 | 3/4 | 89 | Subunit alpha/gamma |
Solute carrier family 38 member 5 | Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides | 100/90 | 14/5 | 73 | Member 5a/b |
Tyrosine 3 monooxigenase | Enzyme function | 90/100 | 5/5 | 74 | Ywhab/ywhag2 |
Set and mynd domain- containing protein 1 | Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation | 95/97 | 154/127 | 76 | Smyd1a/b |
Dual specificity phosphatase and pro Isomerase domain containing 1 | Catalyse reaction: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate. | 95/100 | 7/7 | 51 | DUPD1a/b |
Metalloproteinase inhibitor 2 precursor | Complexes with metalloproteinases and irreversibly inactivates them | 80/60 | 4/4 | 62 | TIMP2b/a |
Retinoid x gamma | Rreceptor for retinoic acid | 100/100 | 21/10 | 73 | Gamma/beta |
Junctophilin 1 | Contributes to the stabilization of the junctional membrane complexes | 85/87 | 7/10 | 65 | Junctophilin 1a/b |
60s ribosomal protein l5 | Required for rRNA maturation and formation of the 60 S ribosomal subunits | 100/100 | 58/186 | 91 | Rpl5a/b |
Trans-2,3-enoyl-CoA reductase | Reduces trans-2,3-stearoyl-CoA to stearoyl-CoA of long and very long chain fatty acids | 98/98 | 11/61 | 75 | Trec.a/b |
Methylmalonate- semialdehyde Dehydrogenase | Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA | 100/100 | 26/12 | 86 | Aldha1.a/a1.b |
Eukaryotic translation initiation factor 4e type 3 | Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 | 100/100 | 28/15 | 73 | EIF4E3a/b |
Fk506-binding protein 1a | May play a role in modulation of ryanodine receptor isoform-1 (RYR-1) | 100/100 | 52/12 | 82 | FKBP1A.1/A.2 |
Splicing arginine serine-rich 11 | May function in pre-mRNA splicing. | 95/95 | 11/25 | 82 | Srf11a/b |
Kelch repeat and btb domain containing 10 | Substrate-specific adapter of an E3 ubiquitin-protein ligase complex | 95/100 | 38/15 | 53 | Kbtb5/kbtb10 |