Figure 8

RNA degradation plot of all probes (panel a) and degradation profile of specifically hybridized probes (b) for microarrays selected from the human tissue data set. Panel a shows the plots obtained using the affy package[16] whereas the curves in panel b are given by the inverse of the degradation function d^S(k)^-1 (see Eq. (10)). The slopes of most of the curves rank in the same order in both panels, except the two curves of steepest slope which reverse order in both parts of the figure owing to the different percentage of absent probes. The percentage of absent probes are %N = 40% (GSM175845), 69% (GSM176301), 50% (GSM175850) and 53% (GSM176120) as determined by the hook method[33, 34]