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Table 4 Distribution and function of additional genes-operons that are putatively linked to GlnR-mediated regulation

From: Comparative genome analysis of central nitrogen metabolism and its control by GlnR in the class Bacilli

species

gene/operon

annotation (literature)

A. flavithermus, G. C56-R3, G. kaustophilus, G. Y412MC61, L. seeligeri, P. JDR2

mcp

regulation of chemotaxis

B. megaterium, G. kaustophilus, G. Y412MC61, P. JDR2, P. polymyxa

pucR

regulation of puc operon (purine catabolism) [20]

B. amyloliquefaciens, B. atrophaeus, B. licheniformis, B. megaterium, B. pumilus

ycsFGI-kipIAR-ycsK

includes regulation of sporulation [63]

B. amyloliquefaciens, B. atrophaeus, L. salivarius

gabP

transport of gamma-aminobutyrate [19]

A. flavithermus, B. cereus, L. rhamnosus, O. oeni, P. JDR2, P. polymyxa, S. gordonii, S. sanguinis

opp, dpp

transport of oligopeptide and/or dipeptide

B. amyloliquefaciens, B. atrophaeus, B. megaterium (2x), B. subtilis, G. kaustophilus, G. Y412MC61

pucI

transport of allantoin

B. amyloliquefaciens, B. atrophaeus (&ywoB), B. subtilis (&ywoB), P. JDR2 (- ywoD)

ywoCD

transport (ywoD) and hydrolysis (ywoC)

B. anthracis, B. cereus, B. thuringiensis, B. weihenstephanensis, P. JDR2 (cpdB only)

K01238<> cpdB

hydrolysis nucleoside 2′,3′-cyclic phosphate + H2O < = > nucleoside 3′-phosphate

L. seeligeri, O. oeni, Pb JDR2, P. polymyxa

ansA,ansZ

L-asparagine + H2O < = > L-aspartate + NH3[38]

B. amyloliquefaciens, B. atrophaeus, B. licheniformis, B. pumilus, B. subtilis

argC

N-Acetyl-L-glutamate 5-semialdehyde < = >

N-Acetyl-L-glutamate 5-phosphate

L. plantarum, L. rhamnosus, L. citreum

aspA

L-aspartate < = > fumarate + NH3

S. mutans, S. gordonii, S. sanguinis, S. suis, S. thermophilus

citZ-citB-idh

conversion of citrate to alpha-ketoglutarate [24]

B. amyloliquefaciens, B. atrophaeus, B. megaterium, B. pseudofirmus, G. C56-T3, G. kaustophilus, G. Y412MC61, P. sp. JDR2

nasDEF

reduction of nitrite to NH3[18]

B. atrophaeus, B. subtilis, G. Y412MC61

pucH

allantoin + H2O < = > allantoate [20]

[pucF: allantoate < = > ureidoglycolate + 2 NH3]

B. anthracis (BC), B. cereus (C), B. thuringiensis (BC), B. weihenstephanensis (C), S. mutans (C)

thrBC

L-homoserine + ATP < = > O-phosphohomoserine + ADP O-phosphohomoserine + H2O < = > threonine + P

ilvA: threonine < = > 2-oxobutanoate + NH3] [24]

B. amyloliquefaciens, B. megaterium, B. pseudofirmus, B. subtilis, P. JDR2

ureABC

urea + H2O < = > CO2 + 2 NH3 [64]

  1. The related data can be found in Additional file 4.