Figure 1

CCT map comparing an E. coli reference sequence to other E. coli genomes. This map was generated by commands 1 to 5 given in Additional file 1A. Starting from the outermost ring the feature rings depict: 1. COG functional categories for forward strand coding sequences; 2. Forward strand sequence features; 3. Reverse strand sequence features; 4. COG functional categories for reverse strand coding sequences. The next 30 rings show regions of sequence similarity detected by BLAST comparisons conducted between CDS translations from the reference genome and 30 E. coli comparison genomes. The last two rings display the GC content and GC skew.