Figure 4

Early pathology and outcome predictor genes. Heat map of all genes with expression profile showing upregulation in HR (A) and LR (B) fish at the mid stage of infection. Further explanations are given in Figure 3. Column “cat” indicates the category of gene annotation according to [10]: V- early antiviral and IFN response, T- T cell response, M- muscle cytoskeleton development, L- lymphocyte regulation, A- apoptosis, I- implicated in immune response, E- mitochondrial electron chain/energy metabolism, O- other/unknown. Genes may have identical name and Refseq ID match, but represent different cDNA sequences on the array (see Additional file 3.)