Figure 4

Gene biotype distribution in transcripts with and without globin reduction. Percentage of identified transcripts in the non-globin reduced and globin-reduced samples; low abundance transcripts consist of transcripts detected at levels too low to be assigned to any of the two previous groups. The 9121 low abundance transcripts contain relatively more processed transcripts, pseudogenes, large intergenic non coding RNAs (lincRNAs) and miscellaneous RNAs (miscRNAs). We statistically compared the distribution of the number of transcripts over the different categories with a chi-square test and all pairwise comparisons were highly significant (p < 2.2e-16).