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Table 2 Top ten most differentially expressed transcripts

From: Increased sensitivity of next generation sequencing-based expression profiling after globin reduction in human blood RNA

Gene Description

Gene name

logConc1

logFC2

pValue

FDR

Pseudogene

CXorf25

-18.79

-14.3

2.10e-54

3.68e-50

Globin Alpha1

HBA1

-5.19

-7.59

7.48e-34

6.53e-30

Globin Alpha2

HBA2

-6.43

-7.51

2.12e-33

1.23e-29

Globin Beta

HBB

-5.99

-6.76

3.82e-29

1.66e-25

Globin Delta

HBD

-12.87

-6.05

4.37e-25

1.52e-21

APX/Shroom Family

SHROOM4

-17.84

-5.37

6.66e-20

1.93e-16

Ataxia/Rad3

ATR

-15.71

4.57

6.80e-17

1.69e-13

Pseudogene

RP11-431J24.4

-21.08

6.1

9.66e-17

2.10e-13

Trub sudouridine synthase

TRUB1

-19.14

4.83

6.43e-16

1.24e-12

Pseudogene

CTD-2165H16.1

-18.82

4.71

1.48e-15

2.58e-12

  1. The 4 most abundant globin transcripts are in the top five of differentially down-regulated transcripts (1 Log Concentration - Overall concentration for a tag across the two groups compared., 2 Log Fold-change - The log-fold change difference for the counts between the groups compared.).
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BMC Genomics

ISSN: 1471-2164

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