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Figure 7 | BMC Genomics

Figure 7

From: Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade

Figure 7

ABMP-induced change in IFN-α production in the large intestine of IQI SPF mice after administration of either water (open circle) or JTX (closed square). a: Amount of IFN-α protein. The release of IFN-α began earlier in JTX-treated mice than in the control mice. b-e: Gene expression of Stat1, Stat2, Isgf3g, which compose an ISGF3 complex, and Irf7. The peak amount of all mRNA expression of Stat2 and Irf7 increased in JTX-treated mice. *p < 0.05. JTX-treated vs. control.

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BMC Genomics

ISSN: 1471-2164

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