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Table 1 miRNAs most preferentially released into EVs

From: Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types

miRNA

Non-transfected cells & EVs

miR-146a - Transfected cells & EVs

 

RPMM cells

RPMM EV

Log2 (EV/Cells)

RPMM cells

RPMM EV

Log2 (EV/Cells)

mir-451

0.4

3945.0

13.3

1.7

7982.5

12.2

mir-150

0.4

2475.0

12.6

0.3

663.0

10.9

mir-146a*

10.4

1321.2

7.0

317863.3*

440496.3*

0.5

mir-320c

24.3

2347.5

6.6

57.8

1803.4

5.0

mir-143

39.9

3232.5

6.3

8327.3

354.4

8.5

mir-720

65.4

3157.5

5.6

3208.9

46.2

5.5

mir-125a-5p

214.7

9360.0

5.4

439.0

2121.6

2.3

mir-486

105.7

3900.0

5.2

72.8

7637.8

6.7

mir-149

89.0

3142.5

5.1

85.3

928.2

3.4

mir-2110

43.5

1380.0

5.0

175.0

928.2

2.4

mir-320a

762.1

23190.0

4.9

1250.0

11483.2

3.2

mir-197

472.4

8347.5

4.1

724.0

6046.6

3.1

mir-339

91.4

1515.0

4.1

178.0

610.0

1.8

mir-99b

2065.2

27420.0

3.7

4900.0

8353.8

0.8

mir-4286

108.5

1245.0

3.5

72.1

1617.7

4.5

mir-92b

515.1

5542.5

3.4

484.0

4800.1

3.3

mir-222

774.1

7882.5

3.3

1200.0

10634.5

3.1

mir-423-5p

5737.2

55762.5

3.3

5290.0

22435.9

2.1

mir-877

467.2

4425.0

3.2

2000.0

2121.6

0.1

mir-191

9501.8

88717.5

3.2

15000.0

40893.8

1.4

mir-1292

140.0

1222.5

3.1

256.0

397.8

0.6

mir-1246

782.8

6570.0

3.1

156.0

11456.6

6.2

  1. Those miRNAs represented by at least 1000 reads in either cells or EV are listed. * For the transfected cells and EVs the RPMM values were calculated after removal of the reads from over-expressed miR-146a, to facilitate comparison with non-transfected samples (the RPMM values shown for miR-146a are those prior to this normalisation).