Treatment-independent miRNA signature in blood of wilms tumor patients

BMC Genomics

Table 1 The 20 most significant miRNAs in Wilms tumor patients before therapy

MiRNA	Log median	Log median	Log difference	Fold	Ttest	Ttest adj	AUC
	Wilms	Control
hsa-miR-20a	10.124	12.929	-2.805	-6.988	7.01E-012	5.94E-009	0.977
hsa-miR-20b	10.057	12.410	-2.353	-5.108	2.49E-011	1.05E-008	0.984
hsa-miR-766	10.079	8.494	1.585	3.000	2.63E-009	3.29E-007	0.033
hsa-miR-144*	7.994	9.524	-1.531	-2.889	2.40E-009	3.29E-007	0.953
hsa-miR-144	8.967	11.506	-2.540	-5.815	2.71E-009	3.29E-007	0.954
hsa-miR-106a	11.506	13.639	-2.132	-4.385	2.14E-009	3.29E-007	0.950
hsa-miR-1246	6.007	2.737	3.270	9.649	1.36E-009	3.29E-007	0.059
hsa-miR-197	11.205	8.888	2.317	4.984	4.33E-009	4.59E-007	0.055
hsa-miR-224	6.403	3.745	2.658	6.310	5.20E-009	4.90E-007	0.043
hsa-miR-18a	9.168	11.205	-2.037	-4.104	6.75E-009	5.72E-007	0.962
hsa-miR-93	10.830	12.766	-1.936	-3.825	8.50E-009	6.55E-007	0.935
hsa-miR-17	11.839	13.273	-1.434	-2.702	1.20E-008	8.48E-007	0.962
hsa-miR-18b	7.044	8.901	-1.856	-3.621	2.02E-008	1.32E-006	0.982
hsa-miR-126	8.320	11.425	-3.104	-8.601	3.38E-008	2.05E-006	0.944
hsa-miR-520d-3p	4.497	2.134	2.363	5.145	4.13E-008	2.33E-006	0.061
hsa-miR-1305	4.877	6.898	-2.021	-4.058	5.14E-008	2.60E-006	0.966
hsa-miR-373	4.819	1.976	2.843	7.173	5.22E-008	2.60E-006	0.064
hsa-miR-106b	13.004	14.104	-1.100	-2.143	6.24E-008	2.94E-006	0.938
hsa-miR-1204	5.360	3.048	2.312	4.967	1.21E-007	5.42E-006	0.078
hsa-miR-374a	6.473	8.483	-2.010	-4.029	1.39E-007	5.91E-006	0.934

The 20 most significant miRNAs when comparing Wilms patients before therapy to healthy controls. Down-regulated fold-change is indicated by negative values, up-regulated fold-change is indicated by positive values.

ISSN: 1471-2164