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Figure 5 | BMC Genomics

Figure 5

From: Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner

Figure 5

Genome-wide linkage scan for survival rate and mean time to death confirms QTLs on chromosomes 5 and 19. Interval mapping of survival rates (in %) after PR8 infection at day 7 (A), day 8 (B) and day 11 (C) show significant QTLs on chromosomes 5 and 19. Suggestive QTLs are observed on chromosomes 2, 3, 10, 16 and 17. Interval mapping using mean time to death confirmed the significant QTL on chromosome 5 and revealed suggestive QTLs on chromosomes 2, 17 and 19 (D). Interval mapping is shown across the entire genome as blue line representing the LRS scores; green line: DBA/2J alleles increase trait values; red line: C57BL/6J alleles increase trait values. Upper x-axis shows mouse chromosomes, lower x-axis shows physical map in mega bases for each chromosome, y-axis represents LRS score. The horizontal lines mark the genome-wide significant thresholds at p<0.05 (red line) and suggestive thresholds at p<0.37 (gray line).

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