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Figure 6 | BMC Genomics

Figure 6

From: Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner

Figure 6

Composite interval mapping indicates interactions of QTLs on chromosomes 5 and 19. The influence of the markers rs13483633 on chromosome 19 (A, B) and rs13478587 on chromosome 5 (C, D) was factored out and the residual LRS were calculated. Two different traits, survival day 8 (A, C) and mean time of death (B, D) were tested by using the web tool of GeneNetwork. Interval mapping is shown across the entire genome as blue line representing the LRS scores; green line: DBA/2J alleles increase trait values; red line: C57BL/6J alleles increase trait values. Upper x-axis shows mouse chromosomes, lower x-axis shows physical map in mega bases for each chromosome, y-axis represents LRS score. The horizontal lines mark the genome-wide significant thresholds at p<0.05 (red line) and suggestive thresholds at p<0.37 (gray line).

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