Receiver operating curves to assess 3D colocalization of genomic elements for the yeast contact map. Receiver operating curves (ROC) were used to assess 3D colocalization of different genomic elements. Data from Duan et al. (left column) and normalized data (right column) were used. A) Centromeres, Telomeres, early origins of replication give positive signal with both types of data. B) The group of tRNA was assessed for 3D colocalization. Two clusters proposed by were assessed with both data: cluster 1 of tRNA genes proposed to colocalize near rDNA and cluster 2 of tRNA genes proposed to colocalize near centromeres. The data from give a positive signal contrary to the data normalized with SCN.