Table 1 Top 25 GO.BP affected by both PML knockdown and TNF α treatment
Gene Ontology Biological Process (GO.BP) | PML Knockdown | TNFα | ||
|---|---|---|---|---|
Gene number | q value | Gene number | q value | |
Cellular metabolic process | 539 | 3.04E-116 | 296 | 9.50E-52 |
Primary metabolic process | 527 | 4.97E-104 | 287 | 1.06E-44 |
Regulation of cellular process | 449 | 1.71E-75 | 301 | 1.92E-60 |
Macromolecule metabolic process | 441 | 1.25E-81 | 237 | 7.06E-34 |
Biopolymer metabolic process | 433 | 7.96E-80 | 230 | 6.54E-32 |
Cellular macromolecule metabolic process | 413 | 1.71E-78 | 219 | 1.87E-31 |
Cellular biopolymer metabolic process | 403 | 4.47E-75 | 210 | 2.56E-28 |
Biosynthetic process | 294 | 9.75E-49 | 160 | 3.39E-21 |
Cell communication | 288 | 5.37E-52 | 219 | 2.97E-56 |
Cellular biosynthetic process | 288 | 9.70E-48 | 155 | 4.47E-20 |
Nitrogen compound metabolic process | 274 | 6.66E-39 | 144 | 7.73E-15 |
Signal transduction | 260 | 4.09E-45 | 201 | 3.61E-51 |
Protein metabolic process | 253 | 7.52E-57 | 141 | 2.06E-27 |
Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 240 | 9.74E-31 | 119 | 1.98E-09 |
Macromolecule biosynthetic process | 230 | 5.36E-35 | 120 | 2.81E-13 |
Cellular protein metabolic process | 229 | 1.32E-56 | 125 | 4.20E-26 |
Cellular macromolecule biosynthetic process | 228 | 1.25E-34 | 117 | 2.02E-12 |
Gene expression | 211 | 5.35E-24 | 118 | 3.60E-11 |
Cellular biopolymer biosynthetic process | 209 | 3.83E-30 | 106 | 1.96E-10 |
Biopolymer biosynthetic process | 209 | 5.59E-30 | 106 | 2.34E-10 |
Transport | 201 | 1.57E-37 | 124 | 1.35E-23 |
Regulation of metabolic process | 197 | 1.26E-21 | 137 | 3.76E-20 |
Multicellular organismal development | 193 | 5.30E-36 | 159 | 7.97E-46 |
Regulation of cellular metabolic process | 187 | 5.51E-20 | 127 | 1.92E-17 |
Regulation of macromolecule metabolic process | 173 | 5.31E-17 | 121 | 1.72E-16 |