Table 5 Top 15 genes interactively regulated by PML knockdown and TNF α treatment
Refseq | Entrez | Symbol | Definition | siC.T-siC.U | siP.T-siP.U | siP.U-siC.U | siP.T-siC.T | siP∗T |
|---|---|---|---|---|---|---|---|---|
NM_002996.3 | 6376 | CX3CL1 | Chemokine (C-X3-C motif) ligand 1 | 8.88 | 88.86 | 0.14 | 1.40 | 10.00 |
NM_006398.2 | 10537 | UBD | Ubiquitin D | 7.74 | 73.62 | 0.95 | 9.07 | 9.51 |
NM_000450.1 | 6401 | SELE | Selectin E (endothelial adhesion molecule 1) | 33.57 | 293.72 | 0.78 | 6.83 | 8.75 |
NM_020311.1 | 57007 | CMKOR1 | Chemokine orphan receptor 1 | 1.30 | 9.84 | 0.26 | 1.99 | 7.56 |
NM_001007595.1 | 388125 | NLF2 | Nuclear localized factor 2 | 1.40 | 8.14 | 0.60 | 3.48 | 5.79 |
NM_152851.1 | 64231 | MS4A6A | Membrane-spanning 4-domains, subfamily A, member 6A, transcript variant 3 | 0.18 | 0.99 | 0.23 | 1.27 | 5.51 |
NM_006623.2 | 26227 | PHGDH | Phosphoglycerate dehydrogenase | 0.19 | 0.98 | 0.51 | 2.61 | 5.17 |
NM_052941.2 | 115361 | GBP4 | Guanylate binding protein 4 | 2.82 | 14.26 | 0.26 | 1.31 | 5.05 |
NM_006332.3 | 10437 | IFI30 | Interferon, gamma-inducible protein 30 | 1.64 | 8.07 | 0.60 | 2.97 | 4.93 |
NM_000963.1 | 5743 | PTGS2 | Prostaglandin-endoperoxide synthase 2 | 6.42 | 29.70 | 0.32 | 1.48 | 4.63 |
NM_004915.3 | 9619 | ABCG1 | ATP-binding cassette, sub-family G, member 1 | 1.02 | 3.74 | 0.34 | 1.25 | 3.68 |
NM_001024465.1 | 6648 | SOD2 | Superoxide dismutase 2, mitochondrial, nuclear gene encoding mitochondrial protein | 14.96 | 54.60 | 0.85 | 3.08 | 3.65 |
NM_003046.2 | 6542 | SLC7A2 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 25.69 | 93.30 | 0.76 | 2.75 | 3.63 |
NM_002970.1 | 6303 | SAT1 | Spermidine/spermine N1-acetyltransferase 1 | 1.01 | 3.56 | 0.62 | 2.18 | 3.53 |
NM_003855.2 | 8809 | IL18R1 | Interleukin 18 receptor 1 | 2.23 | 7.74 | 0.63 | 2.18 | 3.46 |
NM_017413.3 | 8862 | APLN | Apelin | 1.28 | 0.18 | 3.71 | 0.52 | 0.14 |
NM_001255.1 | 991 | CDC20 | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 0.98 | 0.16 | 35.74 | 5.99 | 0.16 |
NM_199160.1 | 26468 | LHX6 | LIM homeobox 6 | 0.49 | 0.10 | 0.95 | 0.19 | 0.20 |
NM_001067.2 | 7153 | TOP2A | Topoisomerase II alpha | 0.90 | 0.19 | 15.98 | 3.32 | 0.21 |
NM_005733.1 | 10112 | KIF20A | Kinesin family member 20A | 0.99 | 0.22 | 8.03 | 1.76 | 0.22 |
NM_016242.2 | 51705 | EMCN | Endomucin | 0.38 | 0.09 | 0.59 | 0.14 | 0.23 |
NM_004701.2 | 9133 | CCNB2 | Cyclin B2 | 1.04 | 0.25 | 10.86 | 2.53 | 0.24 |
NM_018136.2 | 259266 | ASPM | Asp (abnormal spindle)-like, microcephaly associated (Drosophila) | 0.92 | 0.22 | 10.06 | 2.41 | 0.24 |
NM_181803.1 | 11065 | UBE2C | Ubiquitin-conjugating enzyme E2C | 0.96 | 0.23 | 24.06 | 5.95 | 0.24 |
NM_003186.3 | 6876 | TAGLN | Transgelin | 3.67 | 0.91 | 0.85 | 0.23 | 0.27 |
NM_015234.3 | 221395 | GPR116 | G protein-coupled receptor 116 | 1.04 | 0.29 | 1.07 | 0.30 | 0.28 |
NM_014750.3 | 9787 | DLG7 | discs, large homolog 7 (Drosophila) | 1.00 | 0.30 | 6.53 | 1.96 | 0.30 |
NM_003981.2 | 9055 | PRC1 | Protein regulator of cytokinesis 1 | 0.99 | 0.29 | 9.94 | 2.92 | 0.30 |
NM_016359.2 | 51203 | NUSAP1 | Nucleolar and spindle associated protein 1 | 0.97 | 0.29 | 11.76 | 3.40 | 0.30 |
NM_018131.3 | 55165 | CEP55 | centrosomal protein 55kDa | 1.00 | 0.31 | 9.62 | 2.91 | 0.30 |