Table 1 Top 10 over-expressed genes in livers of laying hens
Protein name [Gallus gallus] | GeneID | Ratio ML/IML | Function (Uniprot) |
|---|---|---|---|
Riboflavin-binding protein precursor | 396449 | 66.9 | Required for the transport of riboflavin to the developing oocyte (future yolk) |
Membrane-bound O-acyltransferase domain-containing protein 2 | 421925 | 50.7 | Phospholipid biosynthetic process: Lysophospholipid acyltransferases catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle |
Vitellogenin-3 precursor | 424534 | 45.9 | Precursor of the egg-yolk proteins that are sources of nutrients during early development of oviparous organisms |
Apovitellenin-1 precursor | 396476 | 42.4 | Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes |
PREDICTED: cathepsin E-A-like/similar to nothepsin | 417848 | 34.8 | Unknown |
Vitellogenin-1 | 424547 | 33.8 | Precursor of the egg-yolk proteins that are sources of nutrients during early development of oviparous organisms |
PREDICTED: dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A | 424133 | 24.1 | Unknown (signal transduction, by homology) |
PREDICTED: nebulin-related-anchoring protein | 423899 | 21.1 | Unknown (actin binding, by homology) |
PREDICTED: uncharacterized protein LOC419301/similar to porin | 419301 | 20.9 | Unknown |
Zona pellucida sperm-binding protein 1 precursor | 395418 | 15.1 | Major component of the peri-vitelline membrane |