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Table 2 Genes co-regulated with ANT1

From: Computational identification of transcriptionally co-regulated genes, validation with the four ANT isoform genes

Gene, ENSG ID

Encoded protein (EnsEMBL)

Protein function (UniProt)

ANO1

Anoctamin-1

Ca++-activated chloride channel, higher levels in liver and skeletal muscle

131620

 

ARRDC3

Arrestin domain-containing protein 3

Associated with plasma membrane, highly expressed in skeletal muscle

113369

 

ATP5B*

ATP synthase, beta polypeptide

H + transporting, mitochondrial F1 complex

110955

 

ATP5D

ATP synthase subunit δ, mitochondrial

Mitochondrial membrane ATP synthase

99624

 

ATP13A4

Cation-transporting ATPase 13A4

ATP + H2O = ADP + phosphate; expressed in heart, placenta, liver, skeletal muscles

127249

 

CBY1*

Protein chibby homolog 1

Expressed at higher levels in heart, skeletal muscle

100211

 

COQ7*

Ubiquinone biosynthesis protein COQ7

Involved in ubiquinone biosynthesis, expressed in heart and skeletal muscle

167186

 

COX6B2*

Cytochrome c oxidase subunit VIb 2

Connects the two mitochondrial COX monomers into the physiological form

160471

 

COX7B*

cytochrome c oxidase subunit VIIb

One of the nuclear-coded polypeptide chains of cytochrome c oxidase

131174

 

MYO1F*

Myosin IF

Myosins are actin-based motor molecules with ATPase activity

142347

 

NDUFA9

NADH dehydrogenase 1 α- subcomplex, 9

Subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase

139180

 

NDUFS1*

NADH-ubiquinone oxido- reductase 75 kDa subunit

Subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase

23228

 
  1. Several constructed models of the ANT1 promoter region were screened as described in Figure 1 either on the full chromosomal human sequences or the human promoter library (results with an asterisk). Genes in bold are shown overexpressed in microarrays ( Additional file 3). Gene IDs are with 15 numbers (ex. ENSG00000023228).
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BMC Genomics

ISSN: 1471-2164

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