Table 1 Antagonistically linked traits
Disease | Abbr. | Antagonistically Linked Traits (Loci) | # |
|---|---|---|---|
CROHN DISEASE | CD | AST (17q12); T1D (1p13, 16p11); VIT (1p13); T2D (2p21); RA (1p13); SLE (1p13); PS (19p13); MS (17q21) | 8 |
ASTHMA | AST | CD (17q12); UC (17q12); BLC (17q12); RA (17q12); PS (5q31) | 5 |
GLIOMA | GLI | COR (9p21); T2D (9p21); GLA (9p21); IPF (5p15) ; TN (5p15) | 5 |
ARTHRITIS, RHEUMATOID | RA | AST (17q12); MS (20q13); CD (1p13) | 3 |
MULTIPLE SCLEROSIS | MS | RA (20q13); HCC (1p36); CD (17q21) | 3 |
COLITIS, ULCERATIVE | UC | AST (17q12); CeD (1p36); SLE (1q23) | 3 |
LUNG NEOPLASMS | LN | PN (5p15); IPF (5p15); TN (5p15) | 3 |
TESTICULAR NEOPLASMS | TN | GLI (5p15); LN (5p15) | 2 |
VITILIGO | VIT | CD (1p13); MEL (11q14) | 2 |
DIABETES MELLITUS, TYPE 1 | T1D | CD (1p13, 16p11); IBD (1p13) | 2 |
DIABETES MELLITUS, TYPE 2 | T2D | GLI (9p21); CD (2p21) | 2 |
CELIAC DISEASE | CeD | UC (1p36); CRC (3q26) | 2 |
IDIOPATHIC PULMONARY FIBROSIS | IPF | GLI (5p15); LN (5p15) | 2 |
PSORIASIS | PS | AST (5q31); CD (19p13) | 2 |
LUPUS ERYTHEMATOSUS, SYSTEMIC | SLE | CD (1p13); UC (1q23) | 2 |
GLAUCOMA | GLA | GLI (9p21) | 1 |
MELANOMA | MEL | VIT (11q14) | 1 |
PANCREATIC NEOPLASMS | PN | LN (5p15) | 1 |
ALCOHOLISM | ALC | HNN (12q24) | 1 |
COLORECTAL NEOPLASMS | CRC | CeD (3q26) | 1 |
INFLAMMATORY BOWEL DISEASES | IBD | T1D (16p11) | 1 |
CARCINOMA, HEPATOCELLULAR | HCC | MS (1p36) | 1 |
LIVER CIRRHOSIS, BILIARY | BLC | AST (17q12) | 1 |
CORONARY DISEASE | COR | GLI (9p21) | 1 |
HEAD AND NECK NEOPLASMS | HNN | ALC (12q24) | 1 |