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Figure 1 | BMC Genomics

Figure 1

From: Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR

Figure 1

MACS analysis for LRH-1 ChIP-seq. (A) Summary of ChIP-seq analysis for LRH-1 binding to DNA in hepatic chromatin by MACS. Given mfold 32 and sonication size (bw) 300 bp, MACS searched 2bw window area across the genome to find genomic peaks with tags more than mfold enriched relative to a random tag genome distribution. The results were obtained using the parameters of p-value cutoff 1 × 10-10 and false discovery rate (FDR) 1%. (B) Peak model built by MACS. MACS estimated the d for LRH-1 ChIP-seq data.

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