Is the C-terminal insertional signal in Gram-negative bacterial outer membrane proteins species-specific or not?

BMC Genomics

Table 1 Dataset classified based on OMP class

OMP class	# of β-strands	Total # of peptides	OMP class found in # of organisms in different proteobacteria class					Function/Protein family
OMP class	# of β-strands	Total # of peptides	α	β	γ	δ	ɛ	Function/Protein family
OMP.8	8	2300	71	77	227	24	10	Membrane anchors[15]
OMP.10	10	95	5	2	66	2	2	Bacterial proteases[16]
OMP.12	12	1550	60	75	212	18	10	Integral membrane enzymes[15]
OMP.14	14	572	47	38	221	20	22	Long chain fatty acid transporter[17]
OMP.16	16	2477	41	86	210	23	8	General porins[15]
OMP.18	18	327	2	14	134	7	1	Substrate specific porins[15]
OMP.22	22	7462	71	86	231	25	23	TonB-dependent receptors[15]
OMP.nn	Not known	7591	71	86	231	26	23	-
OMP.hypo	Not known	73	2	18	33	9	1	-

The OMP class of a protein was predicted by HHomp[14]. HHOmp defines the class based on the similarity to a closely related OMP structure. When HHomp cannot find a related structure, it classifies the proteins in OMP.nn. OMP.hypo proteins are hypothetical proteins[14].

ISSN: 1471-2164