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Table 2 List of fourteen candidate genes with related Gene Ontology (GO) categories

From: Toward understanding the genetic basis of adaptation to high-elevation life in poikilothermic species: A comparative transcriptomic analysis of two ranid frogs, Rana chensinensis and R. kukunoris

Sequence ID

Protein homolog

Ka/Ks ratio

GO category

GO accession

Kuku_seq_14688

Glutathione s-transferase omega 2, GSTO2

1.7284

glutathione metabolic process

GO:0006749

Kuku_seq_38792

Sterol carrier protein 2, SCP2

1.4657

peroxisome organization

GO:0007031

Kuku_seq_19028

Ubiquitin-specific protease 1, USP-1

1.2268

response to UV

GO:0009411

Kuku_seq_38041

Ribosomal L1 domain containing 1,RSL1D1

1.1671

primary metabolic process

GO:0044238

Kuku_seq_19815

Peroxiredoxin-4, PRDX4

1.1484

response to oxidative stress

GO:0006979

Kuku_seq_9362

Mitochondrial translation optimization 1, MTO-1

1.1363

mitochondrial tRNA wobble uridine modification

GO:0070899

Kuku_seq_22135

NADPH oxidase organizer 1, NOXO1

1.0432

NADPH oxidase complex

GO:0043020

Kuku_seq_29724

Aminoacylase-1, ACY1

1.0342

protein catabolic process

GO:0030163

Kuku_seq_10530

DNA repair protein xrcc, XRCC

0.6313

response to hypoxia

GO:0001666

Kuku_seq_19044

4-aminobutyrate aminotransferase, ABAT

0.5899

response to hypoxia

GO:0001666

Kuku_seq_19251

Cytochrome p450 4b1-like, CYP4B1

0.5867

oxygen binding

GO:0019825

Kuku_seq_4377

Glutathione peroxidase 4, GPX4

0.5799

glutathione metabolic process

GO:0006749

Kuku_seq_29173

V-type proton ATPase subunit G 1, V-ATPase G1

0.5173

ATP catabolic process

GO:0006200

Kuku_seq_8042

Cytochrome p450 2f1-like, CYP2F1

0.5062

oxygen binding

GO:0019825

  1. These fourteen genes have Ka/Ks ratio greater than 0.5 and are most likely involved in the adaptation to high-elevation environments.