From: RNA-Seq and molecular docking reveal multi-level pesticide resistance in the bed bug
Mode of resistance | Number | Number in the top 5,000 differentials | qRT-PCR validated | |
---|---|---|---|---|
 |  | Up-regulated | Down-regulated |  |
Metabolic resistance | Â | Â | Â | Â |
Cytochrome P450 | 102 | 19 | 10 | BB_Contig_103, 18015, 19601, 22399 |
ABC transporters | 27 | 8 | 2 | BB_Contig_1346 |
GSTs | 18 | 3 | 1 | NA |
Catalase | 13 | 2 | 0 | NA |
Superoxide dismutase | 6 | 1 | 1 | BB_Contig_49102 |
Carboxylesterases | 6 | 2 | 0 | NA |
Glutathione peroxidase | 7 | 3 | 0 | NA |
Penetration resistance | Â | Â | Â | Â |
Cuticular proteins | 247 | 46 | 8 | BB_Contig_1762,1766, 17694, 21630, 48951 |
Insecticidal targets | Â | Â | Â | Â |
Acetylcholinesterases | 6 | 3 | 0 | BB_Contig_3653 |