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Table 1 Overrepresented GO terms in the predicted LEF1/TCF target genes

From: Novel β-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability

GO term

Number of genes

p value

Three top terms

Neuron differentiation

67

1.9E-27

Pattern specification

45

3.4E-21

Sequence-specific DNA binding

60

4.7E-21

Selection of other expected terms

Regulation of cell development

35

1.7E-14

Cell migration

33

8.0E-12

Cell proliferation

26

1.75E-7

Cell adhesion

35

1.4E-6

Regulation of cell death

43

9.6E-6

Wnt receptor signaling pathway

11

2.0E-4

Selection of novel terms related to neuronal function

Synapse

32

3.6E-8

Gated-channel activity

20

2.8E-4

  1. The p values are based on DAVID Bioinformatics Resources (see Materials and Methods).