Table 1 Feature summary of the top 10% highest expressed genes in the oocysts*
Major Category (Genes #) | Feature Description | Representative Gene and description | Signal | |
|---|---|---|---|---|
Enzyme (20) | Â | Â | Â | Â |
  Energy (3) | Glycolytic enzymes | cgd7_480 | Lactate dehydrogenase (LDH) | 3,064.62 |
  Lipid (1) | Membrane remodeling | cgd8_1150 | Choline-phosphate cytidylyltransferase | 185.50 |
  Nucleotide (4) | Nucleotide metabolic enzymes | cgd5_1470 | Nucleoside-diphosphate kinase domain | 1,562.52 |
  Protein modification (9) | Peptidase, kinase, phosphatase | cgd7_4790 | Ptc7p phosphatase (PP2C family) | 333.12 |
Mitochondrial (2) | lscU-like, F-ATPase headpiece | cgd2_1360 | Mitochondrial ATP synthase β-chain | 351.08 |
Transporter (7) | ABC, ion, nutrients, V-type | cgd3_510 | Putative fucose translocator | 398.70 |
Stress-related (5) | Â | Â | Â | Â |
  Chaperonine (3) | DnaJ, HSP20, HSP90 | cgd3_3770 | HSP90 | 1,229.35 |
  Redox homeostasis (2) | Glutaredoxin/thioredoxin related | cgd2_2540 | Glutaredoxin related protein | 250.42 |
Cytoskeleton (3) | Microfilament elements | cgd5_3160 | Actin | 475.92 |
Membrane (7) | All mucin-like proteins | cgd2_430 | Mucin-like glycoprotein | 1,732.54 |
Cell cycle (1) | Cyclin family protein | cgd7_3780 | Cyclin | 318.54 |
Gene expression (14) | Â | Â | Â | Â |
  Transcription (6) | RNA Pol, transcription factors | cgd3_4150 | Cutinase negative acting protein | 315.25 |
  Translation (8) | Translation factors, RNA helicases, etc. | cgd1_880 | Eukaryotic initiation factor 4A | 889.38 |
Protein degradation (1) | Proteosome/ubiquitin subunits | cgd1_420 | 20S proteasome beta subunit D2 | 168.66 |
Ribosome biogenesis (38) | Â | Â | Â | Â |
  Ribosomal proteins (32) | RPL, RPS, or associated proteins | cgd3_2250 | 60S ribosomal protein L37A | 303.99 |
  rRNA processing (6) | GTPase, ribonucleoprotein, etc. | cgd4_1700 | GNog1p. GTPase | 276.15 |
RNA metabolism (11) | Methylase, Helicase, RNA-splicing, RNA-binding, etc. | cgd7_940 | T22E16.120 SC35-like splicing factor | 871.81 |
DNA metabolism (2) | Methytranferase, DNA-binding | cgd2_3070 | HMG-box protein | 425.65 |
Unknown (82) | Â | Â | Â | Â |
  Conserved domains (18) | Conserved domain-containing | cgd2_200 | Possible apicomplexan-specific protein | 1,742.09 |
  Membrane (15) | Predicted membrane proteins | cgd6_780 | Predicted extracellular protein | 849.61 |
  Unknown (49) | Hypothetical/unknown | cgd3_1570 | Unknown, possible sporozoite antigen | 1,957.29 |